Widespread amphibian skin bacteria chemically inhibit pathogens

Prodigiosin and Violacein are two bacterially produced chemicals that inhibit fungal amphibian pathogens

In a new study, Woodhams and colleagues show that compounds such as prodigiosin and violacein produced by amphibian skin bacteria can inhibit fungal pathogens. Volatile organic compounds were also inhibitory.  The team showed that these bacteria are widespread and potentially useful probiotics.

Woodhams DC, LaBumbard BC, Barnhart KL, Becker MH, Bletz MC, Escobar LA, Flechas SV, Forman ME, Iannetta AA, Joyce MD, Rabemananjara F, Gratwicke B, Vences M, Minbiole KPC. (2017) Prodigiosin, violacein, and volatile organic compounds produced by widespread cutaneous bacteria of amphibians can inhibit two Batrachochytrium fungal pathogens. Microbial Ecology, https://doi.org/10.1007/s00248-017-1095-7


Douglas C. Woodhams, Ph.D.
Assistant Professor
UMass Boston | Department of Biology
100 Morrissey Blvd.
Boston, Massachusetts 02125
Phone: 617-287-6679